Acute Lymphoblastic Leukemia: Etiology, Pathogenesis and Treatments : Etiology, Pathogenesis and Treatments
Severo Vecchione, Luigi Tedesco
Acute lymphoblastic leukemia (ALL) is a malignant disorder of the bone marrow in which a lymphoid precursor cell becomes genetically altered resulting in dysregulated proliferation and clonal expansion of neoplastic cells. It is the most common malignancy in children, representing nearly one third of all pediatric cancers. In this book, the authors present topical research in the study of acute lymphoblastic leukemia including genome wide association studies in pediatric acute lymphoblastic leukemia; mice deficient for the Slp65 signaling protein which is a model for ALL; histone deacetylase inhibitors and maintenance therapy in Ph negative adult acute lymphoblastic leukemia.
Տարի:
2012
Հրատարակում:
1
Հրատարակչություն:
Nova Science Publishers, Incorporated
Լեզու:
english
Էջեր:
251
ISBN 10:
161470905X
ISBN 13:
9781614709053
Սերիաներ:
Cancer Etiology, Diagnosis and Treatments
Ֆայլ:
PDF, 8.63 MB
IPFS:
,
english, 2012